Comparative single-cell lineage bias in human and murine hematopoietic stem cells

The commitment of hematopoietic stem cells (HSC) to myeloid, erythroid, and lymphoid lineages is influenced by microenvironmental cues, and governed by cell-intrinsic and epigenetic characteristics that are unique to the HSC population. To investigate the nature of lineage commitment bias in human...

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Bibliographic Details
Main Authors: Isaac Shamie, Meghan Bliss-Moreau, Jamie Casey Lee, Ronald Mathieu, Harold M. Hoffman, Bob Geng, Nathan E. Lewis, Yanfang Peipei Zhu, Ben A. Croker
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-07-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12181
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