AICAR-Induced AMPK Activation Inhibits the Noncanonical NF-κB Pathway to Attenuate Liver Injury and Fibrosis in BDL Rats

Background. To evaluate the AMP-activated protein kinase- (AMPK-) mediated signaling and NF-κB-related inflammatory pathways that contribute to cholestatic diseases in the bile duct ligation (BDL) rat model of chronic cholestasis and verify the protective role of 5-Aminoimidazole-4-carboxamide1-β-D-...

Full description

Saved in:
Bibliographic Details
Main Authors: Haoyang Zhu, Yichao Chai, Dinghui Dong, Nana Zhang, Wenyan Liu, Tao Ma, Rongqian Wu, Yi Lv, Liangshuo Hu
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2018/6181432
Tags: Add Tag
No Tags, Be the first to tag this record!