De novo acquisition of antibiotic resistance in six species of bacteria

ABSTRACT Bacteria can become resistant to antibiotics in two ways: by acquiring resistance genes through horizontal gene transfer and by de novo development of resistance upon exposure to non-lethal concentrations. The importance of the second process, de novo build-up, has not been investigated sys...

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Bibliographic Details
Main Authors: Xinyu Wang, Alphonse de Koster, Belinda B. Koenders, Martijs Jonker, Stanley Brul, Benno H. ter Kuile
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:Microbiology Spectrum
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Online Access:https://journals.asm.org/doi/10.1128/spectrum.01785-24
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