The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin

The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin

Abstract Background Metastasis causes the majority of cancer-related deaths worldwide. Increasing studies have revealed that circRNAs are associated with the carcinogenesis and metastasis of many cancers. Nevertheless, the biological mechanisms of circRNAs in breast cancer (BC) liver metastasis rema...

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Bibliographic Details
Main Authors: Zehao Wang, Lu Yang, Peng Wu, Xing Li, Yuhui Tang, Xueqi Ou, Yue Zhang, Xiangsheng Xiao, Jin Wang, Hailin Tang
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Molecular Cancer
Subjects:
circROBO1
FUS
KLF5
miR-217
BC
Metastasis
Online Access:https://doi.org/10.1186/s12943-022-01498-9
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https://doi.org/10.1186/s12943-022-01498-9

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