Combining a novel ensemble model and multiplex methylation SNaPshot assays for saliva age prediction and cross-platform data analysis

Combining a novel ensemble model and multiplex methylation SNaPshot assays for saliva age prediction and cross-platform data analysis

Abstract Background DNA methylation is a pivotal biomarker for age prediction. However, most studies focus on blood-derived data, with limited research on saliva, and the inability to directly analyze methylation data across diverse platforms constrains predictive accuracy. Results We identified 10...

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Bibliographic Details
Main Authors: Benyang Xiao, Yuxiang Zhou, Zhirui Zhang, Xindi Wang, Jiali Xiang, Zhixin Lv, Miao Liao, Haibo Luo, Feng Song
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Genomics
Subjects:
DNA methylation
Age prediction
Ensemble model
Cross-platform
Saliva
Online Access:https://doi.org/10.1186/s12864-025-11713-8
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https://doi.org/10.1186/s12864-025-11713-8

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