Association between root canals and gingival sulci microbiota in secondary and persistent endodontic infections

Association between root canals and gingival sulci microbiota in secondary and persistent endodontic infections

Abstract Secondary/persistent endodontic infections (SPEIs) result from failed root canal therapy, causing persistent apical periodontitis. Current diagnostic methods for SPEIs predominantly rely on clinical and radiographic indicators, which often lack adequate sensitivity and specificity. Conseque...

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Main Authors: Dong Hyun Park, Euon Jung Tak, Ok-Jin Park, Hiran Perinpanayagam, Yeon-Jee Yoo, Hyo-Jung Lee, Yun-Seok Jeong, Jae-Yun Lee, Hyun Sik Kim, Jin-Woo Bae, Kee-Yeon Kum, Seung Hyun Han
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Biomarkers
Gingival sulcus
Illumina MiSeq platform
Keystone pathogen
Root canal
Secondary/persistent endodontic infections
Online Access:https://doi.org/10.1038/s41598-025-95522-9
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https://doi.org/10.1038/s41598-025-95522-9

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