Clec12a is required for the pathogenesis of NUP98::NSD1 AML

Clec12a is required for the pathogenesis of NUP98::NSD1 AML

Abstract: NUP98::NSD1 is one of the most recurring nucleoporin 98 (NUP98) fusions in acute myeloid leukemia (AML). NUP98::NSD1 positive AML is often associated with adverse outcomes and poor response to conventional treatments. However, limited studies have been done to identify new potential target...

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Main Authors: Sagarajit Mohanty, Fiorella Charles Cano, Razif Gabdoulline, Courteney K. Lai, Basem Othman, Harish Sudarsanam, Thomas Eder, Florian Grebien, Daniel B. Lipka, Reinhard Henschler, Michael Heuser
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952925002782
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