The Significance of Cellular Senescence Hub Genes in the Diagnosis and Subtype Classification of a Comprehensive Database of Gene Expression in Intervertebral Disc Degeneration

The Significance of Cellular Senescence Hub Genes in the Diagnosis and Subtype Classification of a Comprehensive Database of Gene Expression in Intervertebral Disc Degeneration

ABSTRACT Background Intervertebral disc degeneration (IVDD) is a complex age‐related physiological process, with cellular senescence (CS) being a primary contributing factor. However, the precise role of CS and its associated genes in IVDD remains unclear. Methods In this study, we performed differe...

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Bibliographic Details
Main Authors: Fei Liu, Silong Gao, Ji Yin, Chao Song, Yongliang Mei, Zhaoqiang Wang, Zongchao Liu
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:JOR Spine
Subjects:
bioinformatics
cellular senescence
consensus clustering
immune cell infiltration
intervertebral disc degeneration
Online Access:https://doi.org/10.1002/jsp2.70050
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https://doi.org/10.1002/jsp2.70050

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