Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing

Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing

BackgroundHepatocellular carcinoma (HCC) prognosis continues to be challenging due to tumor heterogeneity and dynamic immunosuppressive microenvironments. Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been...

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Bibliographic Details
Main Authors: Haoming Shen, Yizhi Peng, Qingqing Xie, Yuxi Ren, Junping Hu, Peifang Qin, Yuanxiong Chen, Hao Zeng, Yifan Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
hepatocellular carcinoma
biomarkers
pyroptosis
single-cell RNA sequencing
prognostic model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1595539/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1595539/full

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