The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster.

The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster.

C3G is a guanine nucleotide exchange factor (GEF) and modulator of small G-protein activity, which primarily acts on members of the Rap GTPase subfamily. Via promotion of the active GTP bound conformation of target GTPases, C3G has been implicated in the regulation of multiple cellular and developme...

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Main Authors: Margret Shirinian, Milica Popovic, Caroline Grabbe, Gaurav Varshney, Fredrik Hugosson, Hans Bos, Holger Rehmann, Ruth H Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009403&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009403&type=printable

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