The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice.

The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice.

<h4>Background</h4>Liver-selective thyromimetics have been reported to efficiently reduce plasma cholesterol through the hepatic induction of both, the low-density lipoprotein receptor (LDLr) and the high-density lipoprotein (HDL) receptor; the scavenger receptor class B type I (SR-BI)....

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Main Authors: Ivan Tancevski, Egon Demetz, Philipp Eller, Kristina Duwensee, Julia Hoefer, Christiane Heim, Ursula Stanzl, Andreas Wehinger, Kristina Auer, Regina Karer, Julia Huber, Wilfried Schgoer, Miranda Van Eck, Jonathan Vanhoutte, Catherine Fievet, Frans Stellaard, Mats Rudling, Josef R Patsch, Andreas Ritsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0008722&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0008722&type=printable

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