Early Recognition of Drug-Induced Febrile Neutropenia Leads to an Improved Outcome in the Trauma Intensive Care Unit: A Case Report
Traumatic brain injury necessitates the use of antiepileptics for seizure prophylaxis, which are associated with multiple side effects including neutropenia, which may be dose dependent or idiosyncratic. We report the case of a young male with traumatic brain injury who developed febrile neutropenia...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2024-09-01
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| Series: | Journal of Neuroanaesthesiology and Critical Care |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1789205 |
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| author | Bisman J.K. Khurana Amarjyoti Hazarika Kajal Jain |
| author_facet | Bisman J.K. Khurana Amarjyoti Hazarika Kajal Jain |
| author_sort | Bisman J.K. Khurana |
| collection | DOAJ |
| description | Traumatic brain injury necessitates the use of antiepileptics for seizure prophylaxis, which are associated with multiple side effects including neutropenia, which may be dose dependent or idiosyncratic. We report the case of a young male with traumatic brain injury who developed febrile neutropenia, likely secondary to antiepileptic use. Early recognition and stopping of the drugs with use of granulocyte colony-stimulating factor led to the successful management of the patient. |
| format | Article |
| id | doaj-art-47254b5124584fd3a615f2a603630319 |
| institution | Kabale University |
| issn | 2348-0548 2348-926X |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Neuroanaesthesiology and Critical Care |
| spelling | doaj-art-47254b5124584fd3a615f2a6036303192025-01-10T23:57:28ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neuroanaesthesiology and Critical Care2348-05482348-926X2024-09-01110320020210.1055/s-0044-1789205Early Recognition of Drug-Induced Febrile Neutropenia Leads to an Improved Outcome in the Trauma Intensive Care Unit: A Case ReportBisman J.K. Khurana0Amarjyoti Hazarika1https://orcid.org/0000-0001-6563-1477Kajal Jain2Department of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaDepartment of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, IndiaTraumatic brain injury necessitates the use of antiepileptics for seizure prophylaxis, which are associated with multiple side effects including neutropenia, which may be dose dependent or idiosyncratic. We report the case of a young male with traumatic brain injury who developed febrile neutropenia, likely secondary to antiepileptic use. Early recognition and stopping of the drugs with use of granulocyte colony-stimulating factor led to the successful management of the patient.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1789205febrile neutropenianeurointensive care settingstraumatic brain injury |
| spellingShingle | Bisman J.K. Khurana Amarjyoti Hazarika Kajal Jain Early Recognition of Drug-Induced Febrile Neutropenia Leads to an Improved Outcome in the Trauma Intensive Care Unit: A Case Report Journal of Neuroanaesthesiology and Critical Care febrile neutropenia neurointensive care settings traumatic brain injury |
| title | Early Recognition of Drug-Induced Febrile Neutropenia Leads to an Improved Outcome in the Trauma Intensive Care Unit: A Case Report |
| title_full | Early Recognition of Drug-Induced Febrile Neutropenia Leads to an Improved Outcome in the Trauma Intensive Care Unit: A Case Report |
| title_fullStr | Early Recognition of Drug-Induced Febrile Neutropenia Leads to an Improved Outcome in the Trauma Intensive Care Unit: A Case Report |
| title_full_unstemmed | Early Recognition of Drug-Induced Febrile Neutropenia Leads to an Improved Outcome in the Trauma Intensive Care Unit: A Case Report |
| title_short | Early Recognition of Drug-Induced Febrile Neutropenia Leads to an Improved Outcome in the Trauma Intensive Care Unit: A Case Report |
| title_sort | early recognition of drug induced febrile neutropenia leads to an improved outcome in the trauma intensive care unit a case report |
| topic | febrile neutropenia neurointensive care settings traumatic brain injury |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1789205 |
| work_keys_str_mv | AT bismanjkkhurana earlyrecognitionofdruginducedfebrileneutropenialeadstoanimprovedoutcomeinthetraumaintensivecareunitacasereport AT amarjyotihazarika earlyrecognitionofdruginducedfebrileneutropenialeadstoanimprovedoutcomeinthetraumaintensivecareunitacasereport AT kajaljain earlyrecognitionofdruginducedfebrileneutropenialeadstoanimprovedoutcomeinthetraumaintensivecareunitacasereport |