Quantitative Determination of Major Active Components in Polymyxin B Medicinal Products by NMR Spectroscopy

INTRODUCTION. Polymyxin B is a natural multicomponent antibiotic used in its sulfate form for the treatment of infections caused by multidrug-resistant Gram-negative bacteria. Pharmacopoeial standards for polymyxin B medicinal products include limits for the sum of polymyxins B1, B2, B3, and B1-I an...

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Bibliographic Details
Main Authors: N. E. Kuz’mina, S. V. Moiseev, I. Yu. Yakupov, S. I. Kuleshova
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2025-05-01
Series:Регуляторные исследования и экспертиза лекарственных средств
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Online Access:https://www.vedomostincesmp.ru/jour/article/view/744
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