Investigation of the HLA locus in autopsy-confirmed progressive supranuclear palsy

Investigation of the HLA locus in autopsy-confirmed progressive supranuclear palsy

Objectives: Progressive supranuclear palsy (PSP) is a neurodegenerative disease showing pathological tau accumulation in subcortical neurons and glial cells. The human leukocyte antigen (HLA) locus on chromosome 6 is a polymorphic region with complex linkage patterns that has been implicated in seve...

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Main Authors: Jinguo Wang, Shelley L. Forrest, Sathish Dasari, Hidetomo Tanaka, Ekaterina Rogaeva, M. Carmela Tartaglia, Susan Fox, Anthony E. Lang, Subha Kalyaanamoorthy, Gabor G. Kovacs
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Immunobiology
Subjects:
Autoimmune
HLA
IgLON5
Progressive supranuclear palsy
Peptide modelling
Tau
Online Access:http://www.sciencedirect.com/science/article/pii/S0171298525000269
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