Pim1 promotes the maintenance of bone homeostasis by regulating osteoclast function
Abstract The Pim1 (proviral integration site for Moloney leukemia virus 1) protein is a serine/threonine kinase that is essential for cell proliferation, apoptosis and innate immune responses. Here we show that Pim1 promotes osteoclast resorptive function without affecting osteoclast numbers. Specif...
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| Main Authors: | Jeongin Seo, Ryeojin Ko, Minhee Kim, Jeongmin Seo, Hana Lee, Doyong Kim, Woojin Jeong, Han Sung Kim, Soo Young Lee |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-04-01
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| Series: | Experimental and Molecular Medicine |
| Online Access: | https://doi.org/10.1038/s12276-025-01421-4 |
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