Pim1 promotes the maintenance of bone homeostasis by regulating osteoclast function

Abstract The Pim1 (proviral integration site for Moloney leukemia virus 1) protein is a serine/threonine kinase that is essential for cell proliferation, apoptosis and innate immune responses. Here we show that Pim1 promotes osteoclast resorptive function without affecting osteoclast numbers. Specif...

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Bibliographic Details
Main Authors: Jeongin Seo, Ryeojin Ko, Minhee Kim, Jeongmin Seo, Hana Lee, Doyong Kim, Woojin Jeong, Han Sung Kim, Soo Young Lee
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01421-4
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