Tumor-secreted galectin-3 suppresses antitumor response by inducing IL-10+ B cells

Background Breast cancer is the leading cause of cancer-related deaths among women globally. Tumor-secreted proteins foster an immunosuppressive environment, enabling immune evasion and reducing the effectiveness of antitumor immunity. Interleukin (IL)-10, an immune-regulatory cytokine, is upregulat...

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Bibliographic Details
Main Authors: Tao Huang, Jing Cao, Zhenghao Wu, Mingxuan Li, Peng Zheng, Yunxiao Xiao, Ping Lei, Qianheng Wang, Yibing Lv, Wenhao Niu, Yirui Zhang, Junyi Xiao
Format: Article
Language:English
Published: BMJ Publishing Group 2025-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/5/e011445.full
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