Short Pharmacogenomic Investigation of COMT rs4680 in Analgesic Needs of Pediatric Patients with Congenital Abnormalities: A Cross-Sectional Study

Short Pharmacogenomic Investigation of COMT rs4680 in Analgesic Needs of Pediatric Patients with Congenital Abnormalities: A Cross-Sectional Study

Background: Pain management is a primary concern in pediatric surgical care, particularly in patients with congenital abnormalities. Genetic differences may influence variability in analgesic response. This study aimed to explore the association between catechol-O-methyltransferase (COMT) rs4680 pol...

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Main Authors: Kohar Hari Santoso, Anna Surgean Veterini, Retti Kartika Bakti, Khildan Miftahul Firdaus, Bambang Pujo Semedi, Lucky Andriyanto
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Bali Journal of Anesthesiology
Subjects:
analgesia
child health
comt rs4680
pain
personalized medicine
pharmacogenomic
Online Access:https://doi.org/10.4103/bjoa.bjoa_111_25
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https://doi.org/10.4103/bjoa.bjoa_111_25

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