Synphilin-1 regulates mechanotransduction in rigidity sensing through interaction with zyxin
Abstract Background Synphilin-1 has been studied extensively in the context of Parkinson’s disease pathology. However, the biophysical functions of synphilin-1 remain unexplored. To investigate its novel functionalities herein, cellular traction force and rigidity sensing ability are analyzed based...
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| Main Authors: | Seok Gi Kim, Jinyan Li, Ji Su Hwang, Muhammad Anwar Ul Hassan, Ye Eun Sim, Ju Yeon Lee, Jung-Soon Mo, Myeong Ok Kim, Gwang Lee, Sungsu Park |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12951-025-03429-4 |
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