Synphilin-1 regulates mechanotransduction in rigidity sensing through interaction with zyxin

Abstract Background Synphilin-1 has been studied extensively in the context of Parkinson’s disease pathology. However, the biophysical functions of synphilin-1 remain unexplored. To investigate its novel functionalities herein, cellular traction force and rigidity sensing ability are analyzed based...

Full description

Saved in:
Bibliographic Details
Main Authors: Seok Gi Kim, Jinyan Li, Ji Su Hwang, Muhammad Anwar Ul Hassan, Ye Eun Sim, Ju Yeon Lee, Jung-Soon Mo, Myeong Ok Kim, Gwang Lee, Sungsu Park
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-025-03429-4
Tags: Add Tag
No Tags, Be the first to tag this record!