SimOutbreakSelection: a simulation-based tool to optimise sampling design and analysis strategies for detecting epidemic-driven selection

Abstract Throughout history, populations across species have been decimated by epidemic outbreaks. Recent studies have raised the enticing idea that such outbreaks have led to strong natural selection acting on disease-protective genetic variants in the host population. However, so far few, if any,...

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Bibliographic Details
Main Authors: Cindy G. Santander, Ida Moltke
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61574-8
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