Developing mRNA lipid nanoparticle vaccine effective for cryptococcosis in a murine model

Abstract Cryptococcus neoformans is considered a critical fungal pathogen by the World Health Organization and developing a vaccine for cryptococcosis is a top priority. Here, we employed mRNAs encoding an antigen(s) packaged in lipid nanoparticles (LNPs) to develop vaccines for cryptococcosis. Rema...

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Bibliographic Details
Main Authors: Yeqi Li, Suresh Ambati, Richard B. Meagher, Xiaorong Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-025-01079-z
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