Hyaluronidase: structure, mechanism of action, diseases and therapeutic targets
Abstract Hyaluronidase (HAase), a family of enzymes critical for regulating physiological and pathological states, catalyzes the degradation of hyaluronic acid (HA), a key component of the extracellular matrix (ECM). By modulating ECM composition and cellular signaling pathways, HAase plays a pivota...
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| Main Authors: | Jiamin Lu, Zheng Zhao, Lingli Pan, Hui Wu, Shibing Wang, Xiangmin Tong, Shenghao Wu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-07-01
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| Series: | Molecular Biomedicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43556-025-00299-y |
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