Macropinocytosis regulates cytokine expression through Erk signaling in LPS-stimulated macrophages

Macropinocytosis regulates cytokine expression through Erk signaling in LPS-stimulated macrophages

Macropinocytosis, a type of large-scale endocytosis process, is induced in macrophages by extracellular stimuli, including lipopolysaccharide (LPS). In addition to uptake function, emerging evidence supports a link between macropinocytosis and LPS-induced signal transduction. Following LPS stimulati...

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Bibliographic Details
Main Authors: Li Wang, Yanan Li, Yuxin He, Yuchen Fang, Hitomi Mimuro, Adam C. Midgley, Sei Yoshida
Format: Article
Language:English
Published: Japan Society for Cell Biology 2025-03-01
Series:Cell Structure and Function
Subjects:
macropinocytosis
erk
il-1β
il-10
Online Access:https://www.jstage.jst.go.jp/article/csf/50/1/50_25008/_html/-char/en
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