Network pharmacology approach and experimental verification of earthworm protein in the treatment of diabetes mellitus-induced erectile dysfunction

Network pharmacology approach and experimental verification of earthworm protein in the treatment of diabetes mellitus-induced erectile dysfunction

Background: Diabetes mellitus-induced erectile dysfunction (DMED) is a common complication of diabetes mellitus. Earthworm protein (EWP) is an active protein extracted from the Chinese herbal medicine earthworm, which is used in clinical practice for treating DMED. Objective: To investigate the mech...

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Bibliographic Details
Main Authors: Liming Liu, Yuanfeng Zhang, Aiping Zhang, Rui Yan, Xiaowei Ji, Jiashu Yang, Xinping Wang, Yongze Gao, Xiping Xing
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Traditional and Complementary Medicine
Subjects:
Earthworm protein
Diabetes
Erectile dysfunction
Inflammatory response
NF-κB signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2225411024000671
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