Synthesis of <i>bis</i>-Chalcones Based on Green Chemistry Strategies and Their Cytotoxicity Toward Human MeWo and A375 Melanoma Cell Lines

Synthesis of <i>bis</i>-Chalcones Based on Green Chemistry Strategies and Their Cytotoxicity Toward Human MeWo and A375 Melanoma Cell Lines

Chalcone is an aromatic ketone that forms the central core of many important biological compounds. Chalcone derivatives show various biological activities, especially anti-inflammatory, antibacterial, antioxidant, and anticancer activities, and also inhibit melanoma cell growth. In this study, we sy...

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Bibliographic Details
Main Authors: Dorota Olender, Anna Pawełczyk, Anna Leśków, Katarzyna Sowa-Kasprzak, Lucjusz Zaprutko, Dorota Diakowska
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Molecules
Subjects:
<i>bis</i>-chalcones
Claisen–Schmidt reaction
green chemistry
microwave- and ultrasound-assisted synthesis
cytotoxicity
anticancer activity
Online Access:https://www.mdpi.com/1420-3049/29/21/5171
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