FERMT1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by activating EGFR/AKT/β-catenin and EGFR/ERK pathways

FERMT1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by activating EGFR/AKT/β-catenin and EGFR/ERK pathways

Objective: This study aimed to investigate the effects of fermitin family member 1 (FERMT1) on epithelial-mesenchymal transition (EMT) in hepatocellular carcinoma (HCC) via the EGFR/AKT/β-catenin and EGFR/ERK pathways. Methods: The expression of FERMT1 encoding protein kindlin-1 in HCC tissues was d...

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Bibliographic Details
Main Authors: Wubin Guo, Mengnan Liu, Wei Luo, Jing Peng, Fei Liu, Xin Ma, Li Wang, Sijin Yang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Translational Oncology
Subjects:
FERMT1
Epithelial mesenchymal transition
Hepatocellular carcinoma
EGFR/AKT/β-catenin and EGFR/ERK pathways
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324002717
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