Transposable elements may enhance antiviral resistance in HIV-1 elite controllers

Abstract Background Less than 0.5% of people living with HIV-1 are elite controllers (ECs)—individuals who maintain undetectable plasma viremia without antiretroviral therapy, despite having replication-competent viral reservoirs. While EC CD4+ T cells have been investigated for gene expression sign...

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Bibliographic Details
Main Authors: Manvendra Singh, Sabrina M. Leddy, Luis Pedro Iñiguez, Matthew L. Bendall, Douglas F. Nixon, Cédric Feschotte
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Genome Biology
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Online Access:https://doi.org/10.1186/s13059-025-03484-y
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