CanASM: a comprehensive database for genome-wide allele-specific DNA methylation identification and annotation in cancer

CanASM: a comprehensive database for genome-wide allele-specific DNA methylation identification and annotation in cancer

Abstract Allele-specific DNA methylation (ASM) provides critical insights into the complex genetic and epigenetic mechanisms regulating gene transcription. Emerging evidence suggests that ASM is particularly enriched in gene enhancer regions, and recent studies have demonstrated that ASM is increase...

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Bibliographic Details
Main Authors: Jianmei Zhao, Zeyu Zhao, Hongfei Li, Haojie Yu, Hao Lin, Hanqi Chen, Xuecang Li, Di Liu, Yiming Wang, Guohua Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Genomics
Subjects:
Bioinformatics
Single nucleotide variation
DNA methylation
Gene regulation
Online Access:https://doi.org/10.1186/s12864-025-11849-7
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https://doi.org/10.1186/s12864-025-11849-7

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