INHBA+ macrophages and Pro-inflammatory CAFs are associated with distinctive immunosuppressive tumor microenvironment in submucous Fibrosis-Derived oral squamous cell carcinoma
Abstract Transcriptomic and metabolic profiles of tumor cells and stromal cells in oral squamous cell carcinoma (OSCC)-derived from oral submucosal fibrosis (OSF) (ODSCC) have been reported. However, the complex intercellular regulatory network within the tumor immunosuppressive microenvironment (TI...
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| Main Authors: | Simin Zhao, Yu Zhang, Xiaoqin Meng, Ye Wang, Yahui Li, Hao Li, Xingyu Zhao, Pishan Yang, Shaopeng Liu, Chengzhe Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12885-025-14261-2 |
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