Integrated Single-Cell Transcriptome Analysis Reveals Novel Insights into the Role of Opioid Signaling in the Pathophysiology of Inflammatory Bowel Disease

Integrated Single-Cell Transcriptome Analysis Reveals Novel Insights into the Role of Opioid Signaling in the Pathophysiology of Inflammatory Bowel Disease

<b>Background/Objectives:</b> Inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), is characterized by chronic gastrointestinal inflammatory diseases with complex etiology and remains a therapeutic challenge due to heterogeneous treatment respo...

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Bibliographic Details
Main Authors: Mudan Zhang, Zhuo Xie, Shenghong Zhang, Gaoshi Zhou
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
single-cell transcriptomics
inflammatory bowel disease
opioid signaling
monocytes
therapeutic response
Online Access:https://www.mdpi.com/2227-9059/13/6/1398
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