The 2-Step Mendelian Randomisation Study Assesses Genetic Causality and Potential Mediators of Periodontal Disease and Atrial Fibrillation

The 2-Step Mendelian Randomisation Study Assesses Genetic Causality and Potential Mediators of Periodontal Disease and Atrial Fibrillation

Introduction and Aims: This study aims to examine the possible causal link between periodontal diseases and atrial fibrillation (AF), with a focus on the modifiable risk factors that facilitate this connection. Method: Firstly, bidirectional and multivariable Mendelian Randomisation (MR) analyses we...

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Bibliographic Details
Main Authors: Xiaohan Zhang, Chengzhong Lian, Shuqing Shi, Jiaran Li, Lianxin Wang, Zezhen Guo, Naixu Liu, Huan Wang, Yuanhui Hu, Bai Du
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:International Dental Journal
Subjects:
Periodontal disease1
Atrial fibrillation2
Cytokines3
Mendelian randomisation4
Mediating pathway5
Online Access:http://www.sciencedirect.com/science/article/pii/S0020653925000036
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