Single-cell and bulk RNA analysis identifies EMT-associated CAF signatures and prognostic model in lung adenocarcinoma

Abstract Background Cancer-associated fibroblasts (CAFs) have gained increasing attention for their role in lung adenocarcinoma (LUAD), particularly in epithelial-mesenchymal transition (EMT), which may play a key role in tumor microenvironment remodeling and cancer progression. This study aims to i...

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Bibliographic Details
Main Authors: He An, Ping An
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-02951-z
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