Biphasic synaptic Ca influx arising from compartmentalized electrical signals in dendritic spines.
Excitatory synapses on mammalian principal neurons are typically formed onto dendritic spines, which consist of a bulbous head separated from the parent dendrite by a thin neck. Although activation of voltage-gated channels in the spine and stimulus-evoked constriction of the spine neck can influenc...
Saved in:
| Main Authors: | Brenda L Bloodgood, Andrew J Giessel, Bernardo L Sabatini |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-09-01
|
| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1000190&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Boosting of synaptic potentials and spine Ca transients by the peptide toxin SNX-482 requires alpha-1E-encoded voltage-gated Ca channels.
by: Andrew J Giessel, et al.
Published: (2011-01-01) -
MCU expression in hippocampal CA2 neurons modulates dendritic mitochondrial morphology and synaptic plasticity
by: Katy E. Pannoni, et al.
Published: (2025-02-01) -
Contribution of individual excitatory synapses on dendritic spines to electrical signaling
by: Ju-Yun Weng, et al.
Published: (2025-07-01) -
Non-allometric expansion and enhanced compartmentalization of Purkinje cell dendrites in the human cerebellum
by: Silas E Busch, et al.
Published: (2025-04-01) -
miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons.
by: Manavendra Pathania, et al.
Published: (2012-01-01)