Biphasic synaptic Ca influx arising from compartmentalized electrical signals in dendritic spines.

Excitatory synapses on mammalian principal neurons are typically formed onto dendritic spines, which consist of a bulbous head separated from the parent dendrite by a thin neck. Although activation of voltage-gated channels in the spine and stimulus-evoked constriction of the spine neck can influenc...

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Bibliographic Details
Main Authors: Brenda L Bloodgood, Andrew J Giessel, Bernardo L Sabatini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1000190&type=printable
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