Regulating chemoresistance and cancer stemness: the CDH17-YAP pathway in distinct cellular states of lung cancer CTC clusters

Regulating chemoresistance and cancer stemness: the CDH17-YAP pathway in distinct cellular states of lung cancer CTC clusters

Abstract Background Drug resistance in metastatic lung cancer significantly contributes to patient mortality. This study explores the role of circulating tumor cells (CTCs), the precursors to metastasis, in driving this resistance. We aim to delineate the unique biological traits of CTC clusters in...

Full description

Saved in:
Bibliographic Details
Main Authors: Zujun Que, Dan Qi, Yun Yang, Wang Yao, Jiajun Liu, Yan Li, Yuanyuan Yu, Luyao Wang, Fangfei Li, Ge Zhang, Erxi Wu, Jianhui Tian
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Cellular & Molecular Biology Letters
Subjects:
Lung cancer
Circulating tumor cells
Cancer stemness
Chemoresistance
CDH17-YAP pathway
Online Access:https://doi.org/10.1186/s11658-025-00696-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s11658-025-00696-9

Similar Items