Chronic Brucellosis Patients Retain Low Frequency of CD4+ T-Lymphocytes Expressing CD25 and CD28 after Escherichia coli LPS Stimulation of PHA-Cultured PBMCs

Chronic brucellosis patients display a defective Th1 response to PHA. We have previously shown that heat-killed B. abortus (HKBA) can downregulate the PHA-induced increase of CD4+/CD25+ and CD14+/CD80+ cells of brucellosis patients. In the present study, we investigate the effect of E. coli LPS, as...

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Bibliographic Details
Main Authors: Panagiotis Skendros, Alexandros Sarantopoulos, Konstantinos Tselios, Panagiota Boura
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2008/327346
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