Isolation, Characterization, and Genomic Analysis of Bacteriophages Against <i>Pseudomonas aeruginosa</i> Clinical Isolates from Early and Chronic Cystic Fibrosis Patients for Potential Phage Therapy

Isolation, Characterization, and Genomic Analysis of Bacteriophages Against <i>Pseudomonas aeruginosa</i> Clinical Isolates from Early and Chronic Cystic Fibrosis Patients for Potential Phage Therapy

<i>Pseudomonas aeruginosa</i> is associated with both community and hospital-acquired infections. It colonizes the lungs of cystic fibrosis (CF) patients, establishing an ecological niche where it adapts and evolves from early to chronic stages, resulting in deteriorating lung function a...

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Main Authors: Hanzada T. Nour El-Din, Maryam Kettal, José C. Granados Maciel, Greg Beaudoin, Umut Oktay, Sabahudin Hrapovic, Subash Sad, Jonathan J. Dennis, Danielle L. Peters, Wangxue Chen
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Microorganisms
Subjects:
<i>Pseudomonas aeruginosa</i>
cystic fibrosis
bacteriophage
lytic phage
antimicrobial resistance
Online Access:https://www.mdpi.com/2076-2607/13/3/511
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