Nicotinamide Inhibits CD4+ T-Cell Activation and Function

Nicotinamide Inhibits CD4+ T-Cell Activation and Function

Chronic inflammation and autoimmune diseases are driven, in part, by the activation of (auto)reactive CD4+ T-cells, highlighting their potential as therapeutic targets for these diseases. Nicotinamide (NAM) has demonstrated anti-inflammatory properties in various disease models and has already demon...

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Bibliographic Details
Main Authors: Lotte Nijhuis, Alejandra Bodelόn, Rianne C. Scholman, Isabelle Houtzager, Lyanne J. P. M. Sijbers, Enric Mocholi, Lucas W. Picavet, Jorg J. A. Calis, Michal Mokry, Sebastiaan J. Vastert, Jorg van Loosdregt
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
NAM
nicotinamide
CD4+ T-cell activation
auto-immune disease
Online Access:https://www.mdpi.com/2073-4409/14/8/560
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https://www.mdpi.com/2073-4409/14/8/560

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