Timing of Naldemedine Initiation and Occurrence of Diarrhea in Patients Receiving Strong Opioid Analgesics: A Retrospective Study

Naldemedine, a peripherally acting μ-opioid receptor antagonist, is used to treat opioid-induced constipation (OIC). However, it causes diarrhea as an adverse effect. This retrospective study aimed to investigate whether the occurrence of diarrhea was dependent on the timing of naldemedine treatment...

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Bibliographic Details
Main Authors: Takuma Matsumoto, Takuya Mura, Tsubasa Wada, Yuki Tsugo, Naoko Mukai, Terutaka Hamaoka, Shuji Horita, Yasushi Semba, Shinichi Watanabe
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmacy
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Online Access:https://www.mdpi.com/2226-4787/13/2/47
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