Comparison of half-dose alteplase and LMWH in intermediate-high risk pulmonary embolism: a single-center observational study

Comparison of half-dose alteplase and LMWH in intermediate-high risk pulmonary embolism: a single-center observational study

Abstract Background and aim The use of thrombolytics in intermediate-high risk pulmonary embolism (PE) remains controversial. This study evaluated the efficacy and safety of half-dose alteplase compared to anticoagulation with LMWH in this group. Material and methods Patients treated with thrombolyt...

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Main Authors: Ömer Selim Selim Unat, Pervin Korkmaz, Akın Çinkooğlu, Özge Can, Elton Soydan, Selen Bayraktaroğlu, Gürsel Çok, Recep Savaş, Funda Karbek Akarca, Sanem Nalbantgil, Celal Çinar, Mehmet Uyar, Kubilay Demirağ, Tahir Yağdi, Çağatay Engin, Münevver Erdinç, Feza Bacakoğlu
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:The Egyptian Heart Journal
Subjects:
Pulmonary embolism
Intermediate-high risk
Thrombolysis
Half-dose alteplase
Low molecular Weight heparin
Real-life study
Online Access:https://doi.org/10.1186/s43044-025-00669-5
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https://doi.org/10.1186/s43044-025-00669-5

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