Targeting SPATS2 in lung adenocarcinoma: implications for prognosis and immune-based therapy

Abstract Background Lung adenocarcinoma (LUAD) is a major contributor to cancer mortality and exhibits high intratumoral heterogeneity. The functional role of SPATS2 in LUAD remains poorly defined. Methods We integrated transcriptomic data from TCGA, GTEx, and GEO databases to evaluate SPATS2 expres...

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Bibliographic Details
Main Authors: Maorong Teng, Fangtao Yan, Jingping Shang, Xiaohua Sun, Yahui Wang, Jian Shen
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-03179-7
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