Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor
Desmoid tumors (deep fibromatosis) of the mesentery are rare mesenchymal tumors. They are often misdiagnosed, especially with a previous history of resection for gastrointestinal stromal tumor (GIST). Immunohistochemistry can help differentiate between these two tumors. In this article, we present a...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2018/1082956 |
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| _version_ | 1832557015038164992 |
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| author | Areen Abdulelah Murshid Hatim Q. Al-Maghraby |
| author_facet | Areen Abdulelah Murshid Hatim Q. Al-Maghraby |
| author_sort | Areen Abdulelah Murshid |
| collection | DOAJ |
| description | Desmoid tumors (deep fibromatosis) of the mesentery are rare mesenchymal tumors. They are often misdiagnosed, especially with a previous history of resection for gastrointestinal stromal tumor (GIST). Immunohistochemistry can help differentiate between these two tumors. In this article, we present a case we had encountered: a Desmoid tumor developing in a patient with a history of GIST 3 years ago. It is the first case of GIST with subsequent development of Desmoid tumor to be reported in Saudi Arabia. We discuss the two entities of Desmoid tumor and GIST by comparing their definitions, clinical presentations, histological features, immunohistochemistry stains, molecular pathogenesis, prognosis, and treatment. We also discuss the relationship between GIST and the subsequent development of Desmoid tumors and compare our case with case reports in literature. |
| format | Article |
| id | doaj-art-457b9210ea9749acb094a58720fdf7f6 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-457b9210ea9749acb094a58720fdf7f62025-02-03T05:43:45ZengWileyCase Reports in Pathology2090-67812090-679X2018-01-01201810.1155/2018/10829561082956Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal TumorAreen Abdulelah Murshid0Hatim Q. Al-Maghraby1Department of Pathology, King Abdulaziz University Hospital, Jeddah, Saudi ArabiaDepartment of Pathology and Laboratory Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Jeddah, Saudi ArabiaDesmoid tumors (deep fibromatosis) of the mesentery are rare mesenchymal tumors. They are often misdiagnosed, especially with a previous history of resection for gastrointestinal stromal tumor (GIST). Immunohistochemistry can help differentiate between these two tumors. In this article, we present a case we had encountered: a Desmoid tumor developing in a patient with a history of GIST 3 years ago. It is the first case of GIST with subsequent development of Desmoid tumor to be reported in Saudi Arabia. We discuss the two entities of Desmoid tumor and GIST by comparing their definitions, clinical presentations, histological features, immunohistochemistry stains, molecular pathogenesis, prognosis, and treatment. We also discuss the relationship between GIST and the subsequent development of Desmoid tumors and compare our case with case reports in literature.http://dx.doi.org/10.1155/2018/1082956 |
| spellingShingle | Areen Abdulelah Murshid Hatim Q. Al-Maghraby Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor Case Reports in Pathology |
| title | Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor |
| title_full | Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor |
| title_fullStr | Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor |
| title_full_unstemmed | Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor |
| title_short | Subsequent Development of Desmoid Tumor after a Resected Gastrointestinal Stromal Tumor |
| title_sort | subsequent development of desmoid tumor after a resected gastrointestinal stromal tumor |
| url | http://dx.doi.org/10.1155/2018/1082956 |
| work_keys_str_mv | AT areenabdulelahmurshid subsequentdevelopmentofdesmoidtumorafteraresectedgastrointestinalstromaltumor AT hatimqalmaghraby subsequentdevelopmentofdesmoidtumorafteraresectedgastrointestinalstromaltumor |