The history behind ALS type 8: from the first phenotype description to the discovery of VAPB mutation

ABSTRACT Over the past 68 years, the Finkel type late-onset adult autosomal dominant spinal muscular atrophy (SMA) that is allelic with amyotrophic lateral sclerosis-8 (ALS8) gained a genotype-phenotype correlation among the motor neuron diseases through the work of groups led by Zatz and Marques Jr...

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Bibliographic Details
Main Authors: Luiz Eduardo NOVIS, Mariana SPITZ, Hélio A. G. TEIVE
Format: Article
Language:English
Published: Thieme Revinter Publicações 2021-06-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2021000800743&tlng=en
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