The type I collagen paradox in PDAC progression: microenvironmental protector turned tumor accomplice
Abstract Type I collagen (Collagen I, Col I), a principal component of the tumor extracellular matrix (ECM) that accounts for 80% of total ECM collagen, has emerged as a crucial factor in tumor biology. Recent research has found that Col I has influenced tumor growth, invasion, migration, and progno...
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| Main Authors: | Qian Li, Cheng Yang, Junqiang Li, Ronglin Wang, Jie Min, Yang Song, Haichuan Su |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
|
| Series: | Journal of Translational Medicine |
| Online Access: | https://doi.org/10.1186/s12967-025-06778-8 |
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