Comprehensive analysis of culture-negative periprosthetic joint infection with metagenomic next-generation sequencing

Comprehensive analysis of culture-negative periprosthetic joint infection with metagenomic next-generation sequencing

ObjectiveThis study aimed to identify the risk factors and microbial profiles of patients with culture-negative periprosthetic joint infection (PJI) using metagenomic next generation sequencing (mNGS) and to compare the clinical characteristics and treatment outcomes of culture-negative PJI (CN PJI)...

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Bibliographic Details
Main Authors: Lan Lin, Jiayu Li, Canhong Zhang, Juncheng Li, Baijian Wu, Zida Huang, Jianhua Lv, Mingzhong Liu, Wenbo Li, Wenming Zhang, Xinyu Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
periprosthetic joint infection
negative microbiological cultures
metagenomic next-generation sequencing
microbiology
risk factors
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1564488/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1564488/full

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