Integrin Targeting and Beyond: Enhancing Cancer Treatment with Dual-Targeting RGD (Arginine–Glycine–Aspartate) Strategies

Integrin Targeting and Beyond: Enhancing Cancer Treatment with Dual-Targeting RGD (Arginine–Glycine–Aspartate) Strategies

Integrins, an important superfamily of cell adhesion receptors, play an essential role in cancer progression, metastasis, and angiogenesis, establishing them as prime targets for both diagnostic and therapeutic applications. Despite their significant potential, integrin-targeted therapies have faced...

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Bibliographic Details
Main Authors: Bojana Bogdanović, Daniel Fagret, Catherine Ghezzi, Christopher Montemagno
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceuticals
Subjects:
RGD-binding integrin
αvβ3
dual targeting
theranostic
solid tumors
PET imaging
Online Access:https://www.mdpi.com/1424-8247/17/11/1556
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