Assessment of Food Effect and pH‐Dependent Drug–Drug Interactions of Fruquintinib in Healthy Subjects

ABSTRACT This two‐sequence, three‐period study (NCT04645940) was designed to evaluate the effect of food and concomitant rabeprazole, a proton pump inhibitor, on the pharmacokinetics (PK) and safety of fruquintinib and its metabolite M11 after a single oral dose of fruquintinib 5 mg in healthy subje...

Full description

Saved in:
Bibliographic Details
Main Authors: Martha Gonzalez, Zhao Yang, William R. Schelman, Xiaofei Zhou, Neeraj Gupta, Caly Chien
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Clinical and Translational Science
Subjects:
Online Access:https://doi.org/10.1111/cts.70168
Tags: Add Tag
No Tags, Be the first to tag this record!