The Anthrax Toxin Lethal Factor in Solution Does Not Have the Protein’s Crystallized Structure

The bacterium <i>Bacillus anthracis</i> secretes three protein exotoxins: Protective Antigen 83 (PA83), Lethal Factor (LF), and Edema Factor (EF). A cleaved form of PA83 (PA63) aids LF and EF entry into the cytoplasm, which leads to anthrax-induced cell death. The Protein Data Bank (PDB)...

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Bibliographic Details
Main Authors: Kenneth A. Rubinson, John J. Kasianowicz
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/17/4/157
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