Sex and genetic background influence intravenous oxycodone self-administration in the hybrid rat diversity panel

Sex and genetic background influence intravenous oxycodone self-administration in the hybrid rat diversity panel

Opioid Use Disorder (OUD) is an ongoing worldwide public health concern. Genetic factors contribute to multiple OUD-related phenotypes, such as opioid-induced analgesia, initiation of opioid use, and opioid dependence. Here, we present findings from a behavioral phenotyping protocol using male and f...

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Bibliographic Details
Main Authors: Eamonn P. Duffy, Jonathan O. Ward, Luanne H. Hale, Kyle T. Brown, Andrew J. Kwilasz, Erika A. Mehrhoff, Laura M. Saba, Marissa A. Ehringer, Ryan K. Bachtell
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Psychiatry
Subjects:
behavioral genetics
opioid
addiction
sex differences
analgesia
operant conditioning
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1505898/full
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https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1505898/full

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